If you've ever been interested in podcasting but you're not sure where to start, Forever Geek has posted an in depth look at getting started with podcasts, including how to put together a ten minute podcast.
Unless you're an experienced talk show host, then you'd need a script or at least an outline to guide your show. Otherwise, you'd have ten minutes of umms, ahhs, and errs which will surely annoy your audience. Some prefer podcasts that are spontaneous, while others prefer clear-cut 'casts with a definite message.
I've seen several podcasting guides before, but this one really does go in depth, down to suggestions for how you spend each second of a ten minute podcast. If you've ever considered starting a podcast of your own, this is the best guide I've seen yet.
Beginner's guide to podcasts and podcasting (plus: how to create a basic podcast of your own) [Forever Geek]